Curriculum Vitae
MD Azizul Hakim
Research Summary
Independent researcher advancing the intersection of neuroscience and artificial intelligence through biologically-inspired computational frameworks. My work focuses on developing neural network architectures that embody biological principles of homeostasis, neuroplasticity, and adaptive repair to achieve robust, resilient, and biologically-faithful artificial intelligence systems. With publications in Nature Portfolio and IEEE conferences, I have demonstrated that integrating mechanisms from biological nervous systems—including calcium-dependent regulation, multi-scale temporal coordination, and self-repair capabilities—substantially enhances the stability and generalization of machine learning models across diverse domains including molecular property prediction, computer vision, and healthcare AI.
Publications
Journal Articles
DOI: 10.1038/s41598-025-09114-8
- Introduced first implementation of homeostatic regulation mechanisms in artificial neural network layers
- Demonstrated superior performance on critical biomedical benchmarks including AIDS, HIV, COX2, and protein analysis datasets
- Established theoretical foundation for biologically-faithful AI architectures through adaptive repair mechanisms
- Validated self-repair capabilities under various perturbation scenarios, advancing robust AI systems
Conference Proceedings
DOI: 10.1109/QPAIN66474.2025.11172203
- Developed BioLogicalNeuron architecture incorporating calcium-dependent regulation and homeostatic control mechanisms
- Achieved 90.42% accuracy on CIFAR-10 (3.77% improvement over baseline), 99.43% on MNIST, and 93.27% on Fashion-MNIST
- Demonstrated that biological principles of neuroplasticity significantly enhance model generalization across diverse visual domains
- Established repair threshold methodology (0.8) maintaining stability metrics above 0.92 through adaptive interventions
DOI: 10.1109/QPAIN66474.2025.11171750
- Designed multimodal AI framework integrating OCR, deep learning, and fine-tuned LLMs for personalized nutrition management
- Implemented hybrid OCR pipeline combining PaddleOCR (English) and Surya (Bengali) with CNN-based fallback system
- Fine-tuned Llama-3.2 model on clinical guidelines to generate health condition-specific dietary recommendations
- Established multilingual, clinically-validated framework for dietary risk mitigation addressing chronic disease prevention
DOI: 10.1109/QPAIN66474.2025.11171860
- Developed self-repairing neural layer architecture with adaptive learning mechanisms for molecular graph classification
- Demonstrated neuroadaptive intelligence principles in scientific computing applications
- Advanced biologically-inspired AI methodologies for drug discovery and molecular property prediction
- Sole-author publication demonstrating independent research capability
Research in Progress
- First implementation of hierarchical temporal coordination spanning milliseconds to hours in neural architectures
- Demonstrates consistent accuracy improvements and elimination of catastrophic failures across molecular, graph, and image domains
- Outperforms both single-scale bio-inspired models and established state-of-the-art methods
- Establishes cross-scale temporal coordination as fundamental principle for building resilient AI systems
Research Interests
- Biologically-Inspired Neural Architectures: Developing computational frameworks that incorporate homeostatic regulation, neuroplasticity, self-repair mechanisms, and multi-scale temporal dynamics inspired by biological nervous systems
- Robust and Resilient AI Systems: Addressing fundamental brittleness of artificial neural networks through bio-inspired stability mechanisms that maintain consistent performance under perturbations, distribution shifts, and adversarial conditions
- Multi-Scale Temporal Coordination: Investigating how coordination across multiple temporal scales enhances computational efficiency, stability, and recovery capabilities in neural systems
- Neuromorphic and Brain-Inspired Computing: Translating principles from neuroscience, systems biology, and evolutionary theory into computational frameworks that advance artificial intelligence capabilities
- AI for Healthcare and Drug Discovery: Applying biologically-principled AI architectures to biomedical domains including molecular property prediction, protein analysis, and personalized medicine
Honors & Recognition
Selected Research Implementations
- Custom PyTorch layer architecture implementing biological feedback mechanisms for network stability
- Graph neural network applications for molecular property prediction on AIDS, HIV, and COX2 datasets
- Self-repair algorithms validated under various perturbation scenarios
- Modular design enabling integration into existing deep learning pipelines
- Multi-agent coordination using CrewAI and LangGraph frameworks for complex decision-making workflows
- Model Context Protocol (MCP) implementation enabling seamless inter-agent communication
- Specialized agent personas with domain expertise in marketing, product, technology, and operations
- Integration of tool-calling capabilities for market research, financial modeling, and technical planning
- Hybrid OCR pipeline with multilingual support (English via PaddleOCR, Bengali via Surya)
- CNN-based food category detection with nutritional database cross-referencing
- Fine-tuned Llama-3.2 model for clinical guideline-based dietary analysis
- RAG system integrating medical literature for evidence-based recommendations
Technical Expertise
Programming Languages
Machine Learning Frameworks
Research Specializations
AI Engineering Tools
Development & Deployment
Education
- Artificial Intelligence & Machine Learning
- Data Structures & Algorithms
- Database Management Systems
- Software Engineering & System Design
- Computer Networks & Operating Systems
Languages
Professional Activities
- Open Source Contributions: Active contributor to biologically-inspired AI research with public implementations on GitHub
- Peer Review: Experienced in academic writing and research methodology aligned with top-tier journal standards
- Technical Communication: Kaggle Notebooks Master demonstrating ability to communicate complex concepts to diverse audiences
- Community Engagement: Participation in competitive AI challenges and national-level competitions
